منابع مشابه
Epidemiology of Osteoarthritis. In: Veterinary Focus 17(3); 2007
0steoarthritis (OA) is a slowly-progressive degenerative joint disease characterized by a loss of joint cartilage and the subsequent exposure of subchondral bone (1). This eventually results in a self-perpetuating insidious disorder characterized by joint pain. New bone formation occurs in response to the chronic inflammation, and local tissue damage in an attempt to limit both movement and pai...
متن کاملInterleukin-17 Can Induce Osteoarthritis in Rabbit Knee Joints Similar to Hulth's Method
Interleukin-17 (IL-17) is closely related to osteoarthritis (OA), but animal studies that employ IL-17 to induce OA are currently lacking. Therefore, this study evaluated the effect of IL-17 in the rabbit knee joint. The right knees served as the control group. The left knees were divided randomly into 4 groups: a Hulth group and 3 IL-17 groups (1-ng, 10-ng, and 50-ng groups). OA was induced in...
متن کاملCorrelation of IL-17 Level in Synovia and Severity of Knee Osteoarthritis
BACKGROUND The aim of this study was to evaluate the role of interleukin-17 (IL-17) level in synovia and its relationship with the severity of knee osteoarthritis (OA). MATERIAL AND METHODS We enrolled 226 OA patients and 106 controls in this study. The symptomatic/radiation severity of OA was assessed by the Western Ontario McMaster University Osteoarthritis Index (WOMAC) pain score/Kellgren...
متن کاملMicroRNA-17-5p contributes to osteoarthritis progression by binding p62/SQSTM1
Autophagy has been reported to be widely involved in the pathogenesis of osteoarthritis (OA). Increasing evidence suggested the important role of microRNAs (miRs) in the progression of OA. However, the functional role of miR-17-5p in OA development has remained to be fully elucidated. First, a mouse model of OA was established and the relative level of miR-17-5p was determined using PCR. Safran...
متن کاملA17 17..17
Early intervention by teams specialising in the treatment of early psychosis has been suggested to enhance outcome in the early phase of psychotic illness. Two papers in the Journal address this topic. The first examines the cost-effectiveness of these services, while the second examines the 5-year outcome of one such service. McCrone and colleagues (pp. 377–382) report that although their spec...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2010
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.99.2497